If your stomach becomes upset when you take doxycycline, you may take it with food or milk. However, taking doxycycline with milk or food may decrease the amount of medication absorbed from your stomach. Talk with your doctor or pharmacist about the best way to take doxycycline.
If you cannot swallow certain delayed-release tablets (Doryx; generics) whole, carefully break up the tablet and sprinkle the contents of the tablet on a spoonful of cold or room temperature (not hot) applesauce. Eat the mixture right away and swallow without chewing. If the mixture cannot be eaten right away it should be discarded. Be careful not to crush or damage any of the pellets while you are breaking up the tablet.
It is also important information to carry with you in case of emergencies. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital.
This type of interaction is well established with certain medications that form chelates with metallic ions such as iron salts, calcium, and magnesium; thus, drug products or foods containing these ions may cause a decrease in the absorption, bioavailability, and efficacy of the object drug. Drug interactions.
In its general statement concerning tetracyclines, the AHFS Drug Information notes that the absorption of tetracycline is reduced by 50% or more in the presence of food or milk, while the absorption of doxycycline may be reduced by up to 20% by food or milk. The editors of this publication add that this effect is not usually significant.
Milk contains approximay 300 mg of calcium/8 oz. of whole milk was reported to reduce the serum level of tetracycline by 50%-60%. These interactions often involve the primary neutralizing compounds found in the antacid formulation, namely aluminum salts, magnesium salts, and calcium carbonate.
Comprehensive alcohol & food interactions for doxycycline.
Acne clindamycin topical, erythromycin topical, minocycline, tretinoin topical, tetracycline, More.
Pregnancy Category Positive evidence of risk.
Subscribe to receive notifications whenever new articles are published.
Available for Android and iOS devices. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.
Some mixtures of medications can lead to serious and even fatal consequences.
Your doctor may be able to prescribe alternatives that do not interact.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Portions of this document last updated: March 01, 2017.
Check out these best-sellers and special offers on books and newsletters from Mayo Clinic.
The presence of other medical problems may affect the use of this medicine. Make sure you l your doctor if you have any other medical problems, especially:.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of doxycycline in the elderly. However, elderly patients are more likely to have kidney, liver, or heart problems which may require caution and an adjustment in the dose for patients receiving doxycycline.
Drug information provided by: Micromedex.
Subscribe to Housecall.
For this medicine, the following should be considered:.
Depending on the brand you get, you may have to take it with or without food. Talk with It is OK to eat foods containing calcium while taking this antibiotic. Considerations. If you are prescribed doxycycline, talk with your doctor about all other medications and supplements you are taking to avoid any adverse interactions.
Talk with your doctor if she prescribes you doxycycline about whether you need to change your calcium intake while on the medication. When taking certain prescription medications, you may need to change your intake of vitamins, minerals or other supplements you usually consume to avoid negative interactions or side effects. Doxycycline is a drug that interacts with multiple substances, including calcium.
Though it is a commonly used supplement, some medications can interact with calcium, including antibiotics like calcium.