Interactions: See Contraindications. Profound hypotension, loss of consciousness with apomorphine. Serotonin syndrome possible esp. with concomitant serotonergic drugs (eg, SSRIs, SNRIs, MAOIs, mirtazapine, fentanyl, lithium, tramadol, IV methylene blue). May antagonize tramadol.
Daily fractionated radiotherapy to abdomen: 8mg 1–2hrs before radiotherapy, then 8mg every 8hrs after 1st dose for each day of radiotherapy. Highly emetogenic chemotherapy: 24mg once 30 mins before start of single-day chemotherapy (multi-day, single-dose not studied). See full labeling. For all: severe hepatic dysfunction: max 8mg/day. Single high-dose fraction radiotherapy to abdomen: 8mg 1–2hrs before radiotherapy, then 8mg every 8hrs after 1st dose for 1–2 days after radiation completed.
Some supplements have been shown to be very hard on the kidneys, most haven't probably even been studied for problems with kidneys- so you could be buying something that is as bad as, say, Tramadol (or worse) but the manufacturer doesn't have to report that, or no-one might have studied it to see.
I have an arthritic dog, I've tried glucosamine/chondritin, and no success (this was before the larger studies showing it doesn't work came out). Fish oil, and keeping her on gentle/short but regular exercise, seems to be the best thing for her- she loves fish so if I see discounted fish in the supermarket I buy it, freeze it, cook it well/debone, and then give it to her.
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I put my dog on a mobility support diet from the vet which was also on the lower end for protein so decent for her kidneys.
If someone is on opiates and they don't have optimal kidney function, this can in and of itself be a problem because the effects of the drug are magnified. That means then the kidneys are more likely to be damaged from the toxicity of that drug. So if you already have impaired kidney function for whatever.
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When this happens, there is the potential for obstruction and damage to the kidneys.
The following are some key things to know regarding the question of whether or not opiates are bad for your kidneys.
If someone is on opiates and they don’t have optimal kidney function, this can in and of itself be a problem because the effects of the drug are magnified.
I took my dog home and gave her the tramadol and rimadyl as prescribed.( after her blood work was taken) She seemed to be feeling a little better initially, but I got a call from the doctor the next day saying her blood work was back and I needed to bring her in for IV fluids because her kidney numbers were high and her red.
I have a one year old cat, he eats well no concerns there, but he is consently. Cat is very thirsty. (7649 views).
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I actually had a question not related to a pet, if that is okay.
(1)Department of Anesthesiology and Reanimation, Mersin University, School of Medicine, Mersin, Turkey. . In this study, histopathological and biochemical changes due to chronic usage of morphine or tramadol in liver and kidney were assessed in rats. Thirty male Wistar rats g) were included.
In this study, histopathological and biochemical changes due to chronic usage of morphine or tramadol in liver and kidney were assessed in rats. Morphine group (n = 10) received morphine intraperitoneally at a dose of 4, 8, 10 mg/kg/day in the first, second and the third ten days of the study, respectively. Serum LDH, BUN and creatinin levels were significantly increased in the morphine group compared to the tramadol group. Normal saline (1 ml) was given intraperitoneally as placebo in the control group (n = 10).