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Okeliten.orgTramadol and blood pressure medication interaction

Drug combinations


5.22.2018 | Makayla Blare

Status: Caution. Note: The 5-MeO class of tryptamines can be unpredictable in their interactions, particularly increasing the risk of unpleasant physical side effects.

The combination is generally unnecessary because of the stimulating effects of psychedelics. Status: Caution. Note: The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops.

Note: MAO Monoamine Oxidase, an enzyme that catalyses the metabolism of many drugs (e.g., DMT, dopamine and serotonin). -B inhibitors can increase the potency and duration of phenethylamines unpredictably, which could be dangerous given the unpredictability of the 2C-T-x series Status: Caution.

Note: Both substances cause ataxia Loss of motor coordination and bring a risk of vomiting and unconsciousness. If the patient falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position. Status: Dangerous.

Note: No unexpected interactions Status: Dangerous.

Place affected patients in the recovery position to prevent vomit aspiration from excess. Note: Both substances potentiate the ataxia Loss of motor coordination and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Status: Unsafe.

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Tramadol and blood pressure medication interaction
Drug combinations

Note: Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences Status: Caution.

Status: Low Risk & Decrease.

Note: Cocaine and 2c-t-x both provide considerable stimulation. When combined they can result in severe vasoconstriction, tachycardia, hypertension, and in extreme cases heart failure.

Status: Low Risk & No Synergy.

Note: MAO Monoamine Oxidase, an enzyme that catalyses the metabolism of many drugs (e.g., DMT, dopamine and serotonin). -B inhibitors can increase the potency and duration of phenethylamines unpredictably Status: Caution.

Status: Caution. Note: Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures.

Status: Low Risk & Synergy.

Note: Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics. Status: Caution. Small amounts can reduce nausea with aMT but take care.

Note: Amphetamines and NBOMes N-Benzyl-Ortho-Methoxy derivatives of psychedelic phenethylamines. The anxiogenic and focusing effects of stimulants are also not good in combination with psychedelics as they can lead to unpleasant thought loops. NBOMes N-Benzyl-Ortho-Methoxy derivatives of psychedelic phenethylamines. are known to cause seizures and stimulants can increase this risk. both provide considerable stimulation. Status: Unsafe. When combined they can result in tachycardia, hypertension, vasoconstriction and in extreme cases heart failure.

Status: Low Risk & No Synergy.

Status: Low Risk & Synergy.

It is extremely important to be safe at all times! See below the graphic for important information regarding specific combinations. This page will always be 'work in progress'. WARNING! For educational purposes: We do not endorse any of these combinations.

Status: Low Risk & No Synergy.

Status: Caution. Note: Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.

Unsafe - There is considerable risk of physical harm when taking these combinations, they should be avoided where possible.

Status: Caution. Note: Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures.

Note: No unexpected interactions, though likely to increase blood pressure but not an issue with sensible doses. Moving around on high doses of this combination may be ill advised due to risk of physical injury.

antagonist A substance that interferes with or inhibits the physiological action of another. which can be unpleasantly intense Status: Unsafe. NMDA antagonists are often dissociatives. MXE Methoxetamine potentiates NBOMes N-Benzyl-Ortho-Methoxy derivatives of psychedelic phenethylamines. Note: As an NMDA N-methyl-D-aspartate receptor.

Note: The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops. The combination is generally unnecessary because of the stimulating effects of psychedelics.

-A inhbitors have some negative reports associated with the combination but there isn't much information available Status: Caution. Note: MAO Monoamine Oxidase, an enzyme that catalyses the metabolism of many drugs (e.g., DMT, dopamine and serotonin). MAO Monoamine Oxidase, an enzyme that catalyses the metabolism of many drugs (e.g., DMT, dopamine and serotonin). -B inhibitors appear to increase the potency of MXE Methoxetamine.

Note: Little information exists about this combination. Status: Caution.

Status: Unsafe. Note: Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.

Status: Unsafe. Note: Details of this combination are not well understood but PCP generally interacts in an unpredictable manner.

Status: Unsafe. Note: High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort.

Note: Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.

Note: Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences Status: Unsafe.

Note: Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences Status: Caution.

Status: Unsafe. Note: The DOx class as psychedelic stimulants have the potential to mask the effects of DXM and could lead to redosing to an unsafe level. DXM can also potentiate DOx resulting in an unpleasantly intense experience.

Note: There is a high risk of memory loss, vomiting and severe ataxia Loss of motor coordination from this combination. Status: Dangerous.

Note: Tramadol is well known to lower seizure threshold and psychedelics raise the risk of seizures. Status: Caution.

Status: Low Risk & No Synergy.

Note: Risk of tachycardia, hypertension, and manic states Status: Caution.

Note: Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences.

Caution should be exercised. Note: Both these classes of compound can interact unpredictably.

Status: Low Risk & Synergy.

Note: No likely interactions Status: Dangerous.

If the user falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position. Status: Caution. Note: Both substances bring a risk of vomiting and unconsciousness.

Status: Dangerous. Note: High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort.

Note: Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences Status: Unsafe.

Status: Caution. Note: Large amounts of either or both may cause strong and somewhat unpredictable experiences, which can be as intense as psychedelics. Cannabis should be saved for towards the end of the MDMA experience if possible, where the psychedelic alike effect won't come to play. Consider rather Set and Setting are good, before you combine these.

have also shown a tendency to cause severe seizures Status: Caution. Note: Tramadol is well known to lower seizure threshold and NBOMes N-Benzyl-Ortho-Methoxy derivatives of psychedelic phenethylamines.

Note: MAO Monoamine Oxidase, an enzyme that catalyses the metabolism of many drugs (e.g., DMT, dopamine and serotonin). -B inhibitors can increase the potency and duration of phenethylamines unpredictably Status: Caution.

Note: This combination can potentiate the effects of the opioid Status: Caution.

both provide considerable stimulation. Note: Cocaine and NBOMes N-Benzyl-Ortho-Methoxy derivatives of psychedelic phenethylamines. Status: Caution. When combined they can result in severe vasoconstriction, tachycardia, hypertension, and in extreme cases heart failure.

Status: Dangerous. If the user falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position. Note: Both substances cause ataxia Loss of motor coordination and bring a very high risk of vomiting and unconsciousness.

Status: Caution. Note: The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops. The combination is generally uneccessary because of the stimulating effects of psychedelics. Combination of the stimulating effects may be uncomfortable.

Note: Stimulants taken with MXE Methoxetamine can lead to hypermanic states much more easily, especially if sleep is avoided.

Status: Low Risk & No Synergy.

Note: Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences Status: Caution.

Note: Both classes of compounds can be unpredictable alone Status: Caution.

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Status: Caution. Note: Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.

Note: Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences. In extreme cases, they can result in severe vasoconstriction, tachycardia, hypertension, and in extreme cases heart failure. Status: Unsafe.

Note: No unexpected interactions. Status: Dangerous.

Status: Low Risk & Synergy.

Note: High doses of caffeine are uncomfortable and this will be magnified by psychedelics Status: Unsafe.

Note: The combined stimulating effects of the two can lead to an uncomfortable body-load, while the focusing effects of cocaine can easily lead to thought loops. Coming down from cocaine while the DOx is still active can be quite anxiogenic Status: Caution.

Note: Both substances raise heart rate, in extreme cases, panic attacks caused by these drugs have led to more serious heart issues. Status: Unsafe.

If the user falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position. Note: Both substances cause ataxia Loss of motor coordination and bring a risk of vomiting and unconsciousness. Status: Dangerous.

Additional research should always be done before combining drugs. Low Risk & Synergy - These drugs work together to cause an effect greater than the sum of its parts, and they aren't likely to cause an adverse or undesirable reaction when used carefully.

Note: No unexpected interactions, though likely to increase blood pressure but not an issue with sensible doses. Moving around on high doses of this combination may be ill advised due to risk of physical injury.

Note: Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics. Status: Unsafe.

If you use this chart or information on your site you must link to the full summaries and display this message. This chart is meant as a quick reference guide and additional research MUST always be done.

Note: aMT is an MAOI Monoamine oxidase inhibitor are drugs that inhibit the action of monoamine oxidase in the brain and so allow monoamines to accumulate. Using enzyme inhibitors can greatly reduce predictability of effects. on its own.

Note: The 5-MeO psychedelics can interact unpredictably to potentiate other psychedelics Status: Caution.

Status: Caution. Note: The combined stimulating effects of the two can lead to an uncomfortable body-load, while the focusing effects of amphetamine can easily lead to thought loops. Coming down from amphetamines while the DOx is still active can be quite anxiogenic.

Note: There are no reports available about this combination Status: Caution.

Note: Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures. Status: Caution.

Coming down on the MDMA while the DOx is still active can be quite anxiogenic. Note: The combined stimulating effects of the two can be uncomfortable. Status: Unsafe.

Status: Caution. Note: There have been reports of risky serotonergic interactions when the two are taken at the same time, but MXE Methoxetamine taken to the end of an MDMA experience does not appear to cause the same issues.

High doses can cause anxiety which is hard to handle while tripping Status: Unsafe. Note: Caffiene can bring out the natural stimulation from psychedelic drugs to make it uncomfortable.

Note: Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures. Status: Caution.

Note: No expected interactions, some opioids have serotonin A monoamine neurotransmitter, biochemically derived from tryptophan, that is primarily found in the gastrointestinal (GI) tract, plaets, and central nervous system (CNS) of humans and animals. It is a well-known contributor to feelings of well-being. It is a well-known contributor to feelings of well-being. Status: Caution. action, and could lead to Serotonin A monoamine neurotransmitter, biochemically derived from tryptophan, that is primarily found in the gastrointestinal (GI) tract, plaets, and central nervous system (CNS) of humans and animals. These are pretty much only to Pentazocine, Methadone, Tramadol, Tapenatdol. Syndrome or a seizure.

Reactions to these drugs taken in combination are highly unpredictable and have a potential to cause death. Dangerous - These combinations are considered extremely harmful and should always be avoided. Spanish German French Esperanto Portuguese (Needs Translation) Polish (Needs Translation) Status: Caution.

Note: Depending on the SSRI Selective Serotonin Reuptake Inhibitor this combination can be unpredictable Status: Unsafe.

Note: The 5-MeO class of tryptamines can be unpredictable in their interactions Status: Caution.

Status: Low Risk & Decrease.

MAO Monoamine Oxidase, an enzyme that catalyses the metabolism of many drugs (e.g., DMT, dopamine and serotonin). -A inhbitors have some negative reports associated with the combination but there isn't much information available Status: Caution. Note: MAO Monoamine Oxidase, an enzyme that catalyses the metabolism of many drugs (e.g., DMT, dopamine and serotonin). -B inhibitors appear to increase the potency of Ketamine.

Note: MAO Monoamine Oxidase, an enzyme that catalyses the metabolism of many drugs (e.g., DMT, dopamine and serotonin). -B inhibitors can increase the potency and duration of phenethylamines unpredictably Status: Caution.

Note: High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort. Status: Caution.

Note: Both substances raise heart rate, in extreme cases, panic attacks caused by these drugs have led to more serious heart issues.

Note: Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences Status: Unsafe.

Note: No unexpected interactions, though likely to increase blood pressure but not an issue with sensible doses. Status: Caution. Moving around on high doses of this combination may be ill advised due to risk of physical injury.

Note: The focus and anxiety caused by stimulants is magnified by psychedelics and results in an increased risk of thought loops.

Status: Low Risk & No Synergy.

Status: Unsafe. Note: No unexpected interactions.

They will also allow you to drink past a point where you might normally pass out, increasing the risk. Note: Drinking on stimulants is risky because the sedative effects of the alcohol are reduced, and these are what the body uses to gauge drunkenness. This typically leads to excessive drinking with greatly reduced inhibitions, high risk of liver damage and increased dehydration.

Note: Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics. Status: Caution.

Note: Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics. Status: Caution.

Status: Caution. Note: In excess, this combination can cause nausea.

Note: Ketamine and psychedelics tend to potentiate each other - go slowly. Status: Caution.

Note: Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics. Status: Caution.

Status: Low Risk & Synergy.

Note: As an NMDA N-methyl-D-aspartate receptor. MXE Methoxetamine potentiates DOx which can be unpleasantly intense Status: Unsafe. NMDA antagonists are often dissociatives. antagonist A substance that interferes with or inhibits the physiological action of another.

Note: Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics. Status: Caution.

Note: Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences.

Note: Little information exists about this combination. Status: Unsafe.

Status: Caution. Note: High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort.

The combination is generally unnecessary because of the stimulating effects of psychedelics. Combination of the stimulating effects may be uncomfortable. Note: The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops.

Note: High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating it may cause some physical discomfort.

Note: High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort.

Note: Some of the 5-MeO tryptamines are a bit unpredictable and should be mixed with MDMA with care Status: Unsafe.

Status: Caution. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Note: Both substances potentiate the ataxia Loss of motor coordination and sedation caused by the other and can lead to unexpected loss of consciousness at high doses.

This combination is best avoided Status: Caution. Note: The 5-MeO class of tryptamines can be unpredictable in their interactions and the NBOMes N-Benzyl-Ortho-Methoxy derivatives of psychedelic phenethylamines. are known to be unpredictable even alone.

Status: Low Risk & No Synergy.

Note: aMT has a broad mechanism of action in the brain and so does alcohol so the combination can be unpredictable.

Care should be taken when choosing to use this combination. Extreme use may cause physical health issues. Caution - These combinations are not usually physically harmful, but may produce undesirable effects, such as physical discomfort or overstimulation. Synergistic effects may be unpredictable.

Status: Low Risk & No Synergy.

Status: Low Risk & No Synergy.

The combination is unlikely to cause any adverse or undesirable reaction beyond those that might ordinarily be expected from these drugs. Low Risk & No Synergy - Effects are just additive.

Note: The focus and anxiety caused by stimulants is magnified by psychedelics and results in an increased risk of thought loops Status: Caution.

Status: Low Risk & No Synergy.

Note: This combination can cause seizures due to the lowering of the threshold by tramadol and the potential of mescaline to cause seziures. Status: Caution.

Tramadol and blood pressure medication interaction